Matchday 1 : 13-14 September 2011
13 September 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| E | Chelsea |  | 2-0 |  | Leverkusen |
| E | Genk |  | 0-0 |  | Valencia |
| F | Olympiacos |  | 0-1 |  | Marseille |
| F | Dortmund |  | 1-1 |  | Arsenal |
| G | Porto |  | 2-1 |  | Shakhtar Donetsk |
| G | APOEL |  | 2-1 |  | Zenit |
| H | Barcelona |  | 2-2 |  | AC Milan |
| H | Plzeň |  | 1-1 |  | BATE |
14 September 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| A | Man. City |  | 1-1 |  | Napoli |
| A | Villarreal |  | 0-2 |  | Bayern |
| B | Lille |  | 2-2 |  | CSKA Moskva |
| B | Internazionale |  | 1-0 |  | Trabzonspor |
| C | Basel |  | 2-1 |  | Oţelul Galaţi |
| C | Benfica |  | 1-1 |  | Man. United |
| D | Dinamo Zagreb |  | 0-1 |  | Real Madrid |
| D | Ajax |  | 0-0 |  | Lyon |
Matchday 2 : 27-28 September 2011
27 September 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| A | Bayern | | 2-0 | | Man. City |
| A | Napoli | | 2-0 | | Villarreal |
| B | CSKA Moskva | | 2-3 | | Internazionale |
| B | Trabzonspor | | 1-1 | | Lille |
| C | Man. United | | 3-3 | | Basel |
| C | Oţelul Galaţi | | 0-1 | | Benfica |
| C | Lyon | | 2-0 | | Dinamo Zagreb |
| D | Real Madrid | | 3-0 | | Ajax |
28 September 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| E | Valencia |  | 1-1 |  | Chelsea |
| E | Leverkusen | | 2-0 | | Genk |
| F | Arsenal | | 2-1 | | Olympiacos |
| F | Marseille | | 3-0 | | Dortmund |
| G | Zenit | | 3-1 | | Porto |
| G | Shakhtar Donetsk | | 1-1 | | APOEL |
| H | BATE | | 0-5 | | Barcelona |
| H | AC Milan | | 2-0 | | Plzeň |
Matchday 3 : 18-19 October 2011
18 October 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| A | Napoli | | 1-1 | | Bayern |
| A | Man. City | | 2-1 | | Villarreal |
| B | CSKA Moskva | | 3-0 | | Trabzonspor |
| B | Lille | | 1-0 | | Inter Milan |
| C | Oţelul Galaţi | | 0-2 | | Man. United |
| C | Basel | | 0-2 | | Benfica |
| D | Real Madrid | | 4-0 | | Lyon |
| D | Dinamo Zagreb | | 0-2 | | Ajax |
19 October 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| E | Leverkusen | | 2-1 | | Valencia |
| E | Chelsea | | 5-0 | | Genk |
| F | Marseille | | 0-1 | | Arsenal |
| F | Olympiacos | | 3-1 | | Dortmund |
| G | Shakhtar Donetsk | | 2-2 | | Zenit |
| G | Porto | | 1-1 | | APOEL |
| H | AC Milan | | 2-0 | | BATE |
| H | Barcelona | | 2-0 | | Plzeň |
Matchday 4 : 1-2 November 2011
1 November 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| E | Valencia | | 3-1 | | Leverkusen |
| E | Genk | | 1-1 | | Chelsea |
| F | Arsenal | | 0-0 | | Marseille |
| F | Dortmund | | 1-0 | | Olympiacos |
| G | Zenit | | 1-0 | | Shakhtar Donetsk |
| G | APOEL | | 2-1 | | Porto |
| H | BATE | | 1-1 | | Milan |
| H | Plzeň | | 0-4 | | Barcelona |
2 November 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| A | Bayern | | 3-2 | | Napoli |
| A | Villarreal | | 0-3 | | Man. City |
| B | Trabzonspor | | 0-0 | | CSKA Moskva |
| B | Inter Milan | | 2-1 | | Lille |
| C | Man. United | | 2-0 | | Oţelul Galaţi |
| C | Benfica | | 1-1 | | Basel |
| D | Lyon | | 0-2 | | Real Madrid |
| D | Ajax | | 4-0 | | Dinamo Zagreb |
Matchday 5 : 22-23 November 2011
22 November 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| A | Napoli | | 2-1 | | Man. City |
| A | Bayern | | 3-1 | | Villarreal |
| B | CSKA Moskva | | 0-2 | | Lille |
| B | Trabzonspor | | 1-1 | | Inter Milan |
| C | Oţelul Galaţi | | 2-3 | | Basel |
| C | Man. United | | 2-2 | | Benfica |
| D | Real Madrid | | 6-2 | | Dinamo Zagreb |
| D | Lyon | | 0-0 | | Ajax |
23 November 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| E | Leverkusen | | 2-1 | | Chelsea |
| E | Valencia | | 7-0 | | Genk |
| F | Marseille | | 0-1 | | Olympiacos |
| F | Arsenal | | 2-1 | | Dortmund |
| G | Zenit | | 0-0 | | APOEL |
| G | Shakhtar Donetsk | | 0-2 | | Porto |
| H | AC Milan | | 2-3 | | Barcelona |
| H | BATE | | 0-1 | | Plzeň |
Matchday 6 : 6-7 December 2011
6 December 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| E | Chelsea | | 3-0 | | Valencia |
| E | Genk | | 1-1 | | Leverkusen |
| F | Olympiacos | | 3-1 | | Arsenal |
| F | Dortmund | | 2-3 | | Marseille |
| G | Porto | | 0-0 | | Zenit |
| G | APOEL | | 0-2 | | Shakhtar Donetsk |
| H | Barcelona | | 4-0 | | BATE |
| H | Plzeň | | 2-2 | | AC Milan |
7 December 2011
| Grup | Home | Skor | Away | ||
|---|---|---|---|---|---|
| A | Man. City | | 2-0 | | Bayern |
| A | Villarreal | | 0-2 | | Napoli |
| B | Lille | | 0-0 | | Trabzonspor |
| B | Inter Milan | | 1-2 | | CSKA Moskva |
| C | Basel | | 2-1 | | Man. United |
| C | Benfica | | 1-0 | | Oţelul Galaţi |
| D | Dinamo Zagreb | | 1-7 | | Lyon |
| D | Ajax | | 0-3 | | Real Madrid |
